![]() Regenexx, the largest provider of stem cell therapy for orthopaedic conditions in the United States have treated 30,000 patients with stem cell therapy for various joint conditions including knee pain. However, there are already more than 200 published studies related to the use of stem cells in treating orthopaedic conditions. Some doctors and media channels argue that there is very little evidence to support the use of stem cells to treat orthopaedic conditions. Therefore, for an older patient with moderate osteoarthritis, a combination of patient’s own PRP and commercially available exosomes might be a viable and balanced option.ĭiscuss with your doctor and choose the least invasive method to begin with. The lack of DNA makes rejection of these cells impossible so it lowers the risk of their use. The result is a concentration of proteins, messenger RNA (mRNA) and growth factors, without any of the original cell’s DNA. There is a plethora of these commercially available products, ranging from growth factors derived from placental tissues (umbilical cord blood, amniotic fluid, Wharton’s jelly, etc) to stem cells derived from donors.Įxosomes are the result of a purification process of stem cells. The general health of the patient also contributes to the number and quality of stem cells in their tissues.įor a patient who is 50 years old or older, while PRP could be useful, a decision on whether internal sources of stem cells or external sources of stem cells (commercially available regenerative cells derived from healthy donors) to be used will need to be considered. After age 45, the number of stem cells in bone marrow decreases rapidly every year. The age of the patient determines whether patient’s own stem cells are used or not. One advantage of stem cell therapy is the treatments required are less, and potential drawbacks are the cost. If the injuries or osteoarthritis are severe, then stem cells are a better alternative. The need for repeated treatments is somewhat of a disadvantage. The ease of collection and lower cost are advantages. ![]() On the other end of the spectrum are invasive surgical treatments such as bone realignment surgery and total knee replacement (TKR).įor peripheral mild to moderate tendon injuries (partial shoulder rotator cuff tears, shoulder labral tears, tennis/golfer’s elbow, carpal tunnel syndrome, mild hip osteoarthritis, hip labral tears, gluteal or hamstring tears, trochanteric bursitis, mild knee osteoarthritis, mild meniscal tears, ankle ligament sprain, plantar fasciitis and others), platelet-rich plasma is usually a good alternative of treatment. In the middle you will have less invasive strategies such as injectables i.e. On one side of the spectrum are non-invasive strategies such as losing weight and appropriate physical therapy to strengthen your muscles and to have proper walking, standing and sitting habits. PRP vs Stem Cells vs ExosomesThere is no one size fits all treatment.
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